SigE: A master regulator of Mycobacterium tuberculosis

SigE: A master regulator of Mycobacterium tuberculosis

The Extracellular function (ECF) sigma factor SigE is one of the best characterized out of the 13 sigma factors encoded in the Mycobacterium tuberculosis chromosome. SigE is required for blocking phagosome maturation and full virulence in both mice and guinea pigs. Moreover, it is involved in the re...

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Bibliographic Details
Main Authors: Riccardo Manganelli, Laura Cioetto-Mazzabò, Greta Segafreddo, Francesca Boldrin, Davide Sorze, Marta Conflitti, Agnese Serafini, Roberta Provvedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
sigma factor
stress response
regulatory network
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1075143/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1075143/full

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