Ebola Virus Activates IRE1α-Dependent <i>XBP1u</i> Splicing

Ebola (EBOV) and Marburg virus (MARV) are highly pathogenic filoviruses that influence cellular signaling according to their own needs. MARV has been shown to regulate the IRE1α-dependent unfolded protein response (UPR) to ensure optimal virus replication. It was not known whether EBOV affects this...

Full description

Bibliographic Details
Main Authors: Cornelius Rohde, Sebastian Pfeiffer, Sara Baumgart, Stephan Becker, Verena Krähling
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/1/122