Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons

Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons

Summary: Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in vivo. Here, we screen RNA-binding proteins for role...

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Bibliographic Details
Main Authors: Anne L. Sapiro, Emily C. Freund, Lucas Restrepo, Huan-Huan Qiao, Amruta Bhate, Qin Li, Jian-Quan Ni, Timothy J. Mosca, Jin Billy Li
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports
Subjects:
A-to-I RNA editing
Adar
Zn72D
neuromuscular junction
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720306070

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http://www.sciencedirect.com/science/article/pii/S2211124720306070

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