A novel 3D bilayer hydrogel tri-culture system for studying functional motor units

A novel 3D bilayer hydrogel tri-culture system for studying functional motor units

Abstract Background A motor unit (MU) is formed by a single alpha motor neuron (MN) and the muscle fibers it innervates. The MU is essential for all voluntary movements. Functional deficits in the MU result in neuromuscular disorders (NMDs). The pathological mechanisms underlying most NMDs remain po...

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Bibliographic Details
Main Authors: Yu-Lung Lin, Jennifer Nhieu, Thomas Lerdall, Liming Milbauer, Chin-Wen Wei, Dong Jun Lee, Sang-Hyun Oh, Stanley Thayer, Li-Na Wei
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell & Bioscience
Subjects:
Motor unit
Motor neuron
Muscle
Schwann cell
Neuromuscular
Hydrogel
Online Access:https://doi.org/10.1186/s13578-023-01115-2

Internet

https://doi.org/10.1186/s13578-023-01115-2

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