Estimating the accuracy of anal cytology in the presence of an imperfect reference standard.

The study aim is to estimate sensitivity and specificity of anal cytology for histologic HSIL in analyses adjusted for the imperfect biopsy reference standard.Retrospective cohort study of an anal dysplasia screening program for HIV infected adults. We estimated the prevalence of histologic HSIL by...

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Bibliographic Details
Main Authors: William C Mathews, Edward R Cachay, Joseph Caperna, Amy Sitapati, Bard Cosman, Ian Abramson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2924391?pdf=render