Bright future or blind alley? CAR-T cell therapy for solid tumors

Bright future or blind alley? CAR-T cell therapy for solid tumors

Chimeric antigen receptor (CAR) T cells therapy has emerged as a significant breakthrough in adoptive immunotherapy for hematological malignancies with FDA approval. However, the application of CAR-T cell therapy in solid tumors remains challenging, mostly due to lack of suitable CAR-T target antige...

Full description

Bibliographic Details
Main Authors: Kai Zhang, Hong Chen, Fuqiang Li, Sheng Huang, Fei Chen, Yi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
CAR-T cells
solid tumor
adoptive immunotherapy
tumor microenvironment
cytokine release syndrome
tumor infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1045024/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1045024/full

Similar Items