Somatic mutations of thymic epithelial tumors with myasthenia gravis

Somatic mutations of thymic epithelial tumors with myasthenia gravis

BackgroundThymic epithelial tumors are rare malignant neoplasms that are frequently associated with paraneoplastic syndromes, especially myasthenia gravis. GTF2I is an oncogene mutated in a subgroup of thymomas that is reputed to drive their growth. However, for GTF2I wild-type tumors, the relevant...

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Main Authors: Eleonora Pardini, Federico Cucchiara, Sara Palumbo, Giulia Tarrini, Alessia Di Vita, Fabio Coppedè, Vanessa Nicolì, Melania Guida, Michelangelo Maestri, Roberta Ricciardi, Vittorio Aprile, Marcello C. Ambrogi, Serena Barachini, Marco Lucchi, Iacopo Petrini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
GTF2I
thymoma
next-generation sequencing
myasthenia gravis
thymic epithelial tumors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1224491/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1224491/full

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