Analysis of Active Compounds Using Target Protein Cofilin―Cucurbitacins in Cytotoxic Plant <i>Bryonia cretica</i>

Analysis of Active Compounds Using Target Protein Cofilin―Cucurbitacins in Cytotoxic Plant <i>Bryonia cretica</i>

We examined a two-step target protein binding strategy that uses cofilin as the target protein to analyze the active constituents in <i>Bryonia cretica</i>. In the first step, we prepared the target protein, and used it to analyze the compounds binding to it in the second step. We used t...

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Bibliographic Details
Main Authors: Souichi Nakashima, Yoshimi Oda, Moeko Morita, Ayako Ohta, Toshio Morikawa, Hisashi Matsuda, Seikou Nakamura
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Toxins
Subjects:
isolation with target protein
cofilin
cucurbitacin
isocucurbitacin D
Online Access:https://www.mdpi.com/2072-6651/14/3/212

Internet

https://www.mdpi.com/2072-6651/14/3/212

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