Data‐driven analysis of JAK2V617F kinetics during interferon‐alpha2 treatment of patients with polycythemia vera and related neoplasms

Data‐driven analysis of JAK2V617F kinetics during interferon‐alpha2 treatment of patients with polycythemia vera and related neoplasms

Abstract Treatment with PEGylated interferon‐alpha2 (IFN) of patients with essential thrombocythemia and polycythemia vera induces major molecular remissions with a reduction in the JAK2V617F allele burden to undetectable levels in a subset of patients. A favorable response to IFN has been argued to...

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Bibliographic Details
Main Authors: Rasmus K. Pedersen, Morten Andersen, Trine A. Knudsen, Zamra Sajid, Johanne Gudmand‐Hoeyer, Marc J. B. Dam, Vibe Skov, Lasse Kjær, Christina Ellervik, Thomas S. Larsen, Dennis Hansen, Niels Pallisgaard, Hans C. Hasselbalch, Johnny T. Ottesen
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Cancer Medicine
Subjects:
early treatment
essential thrombocythemia
interferon‐alpha2
JAK2V617F kinetics
myeloproliferative neoplasms
polycythemia vera
Online Access:https://doi.org/10.1002/cam4.2741

Internet

https://doi.org/10.1002/cam4.2741

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