MiR-378a-3p Acts as a Tumor Suppressor in Colorectal Cancer Stem-Like Cells and Affects the Expression of MALAT1 and NEAT1 lncRNAs

MiR-378a-3p Acts as a Tumor Suppressor in Colorectal Cancer Stem-Like Cells and Affects the Expression of MALAT1 and NEAT1 lncRNAs

MiR-378a-3p plays a critical role in carcinogenesis acting as a tumor suppressor, promoting apoptosis and cell cycle arrest and reducing invasion and drug resistance in several human cancers, including colorectal cancer (CRC), where its expression is significantly associated with histological classi...

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Bibliographic Details
Main Authors: Giorgia Castellani, Mariachiara Buccarelli, Valentina Lulli, Ramona Ilari, Gabriele De Luca, Francesca Pedini, Alessandra Boe, Nadia Felli, Mauro Biffoni, Emanuela Pilozzi, Giovanna Marziali, Lucia Ricci-Vitiani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
MiR-378a-3p
lncRNAs
MALAT1
NEAT1
colorectal cancer
colorectal cancer stem-like cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.867886/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.867886/full

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