The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells.

The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells.

Toscana virus is a major cause of arboviral disease in humans in the Mediterranean basin during summer. However, early virus-host cell interactions and entry mechanisms remain poorly characterized. Investigating iPSC-derived human neurons and cell lines, we found that virus binding to the cell surfa...

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Bibliographic Details
Main Authors: Jana Koch, Qilin Xin, Martin Obr, Alicia Schäfer, Nina Rolfs, Holda A Anagho, Aiste Kudulyte, Lea Woltereck, Susann Kummer, Joaquin Campos, Zina M Uckeley, Lesley Bell-Sakyi, Hans-Georg Kräusslich, Florian Km Schur, Claudio Acuna, Pierre-Yves Lozach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011562

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https://doi.org/10.1371/journal.ppat.1011562

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