Pan-cancer illumination of TRIM gene family reveals immunology regulation and potential therapeutic implications

Pan-cancer illumination of TRIM gene family reveals immunology regulation and potential therapeutic implications

Abstract Background The tripartite motif (TRIM) proteins function as important regulators in innate immunity, tumorigenesis, cell differentiation and ontogenetic development. However, we still lack knowledge about the genetic and transcriptome alterations landscape of TRIM proteins across cancer typ...

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Bibliographic Details
Main Authors: Yueying Gao, Tao Pan, Gang Xu, Si Li, Jing Guo, Ya Zhang, Qi Xu, Jiwei Pan, Yanlin Ma, Juan Xu, Yongsheng Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Human Genomics
Subjects:
TRIM genes
Pan-cancer
Immune pathways
Immunotherapy response
Online Access:https://doi.org/10.1186/s40246-022-00441-9

Internet

https://doi.org/10.1186/s40246-022-00441-9

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