N-Formyl-L-aspartate mediates chemotaxis in sperm via the beta-2-adrenergic receptor

Chemotaxis is a highly conserved physiological event required for directed sperm movement during fertilization. Recently, studies from our laboratory have identified N-formyl-L-aspartate (NFA) as a sperm chemoattractant. NFA is a known agonist for the beta-2-adrenergic receptor (β-2-AR) that regulat...

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Bibliographic Details
Main Authors: Durva Panchal, Shweta Bhagwat, Priyanka Parte
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.959094/full