AAA+ proteases: the first line of defense against mitochondrial damage

Mitochondria play essential cellular roles in Adenosine triphosphate (ATP) synthesis, calcium homeostasis, and metabolism, but these vital processes have potentially deadly side effects. The production of the reactive oxygen species (ROS) and the aggregation of misfolded mitochondrial proteins can l...

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Bibliographic Details
Main Author: Gautam Pareek
Format: Article
Language:English
Published: PeerJ Inc. 2022-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14350.pdf