Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells

ABSTRACT Zika virus (ZIKV) is a mosquito-borne Flavivirus that has emerged as the cause of encephalitis and fetal microencephaly in the Americas. ZIKV uniquely persists in human bodily fluids for up to 6 months, is sexually transmitted, and traverses the placenta and the blood-brain barrier (BBB) to...

Full description

Bibliographic Details
Main Authors: Megan C. Mladinich, John Schwedes, Erich R. Mackow
Format: Article
Language:English
Published: American Society for Microbiology 2017-09-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00952-17