Crocin attenuates osteoclastogenesis and enhances bone health by skewing the immunoporotic “Treg-Th17” cell axis in post-menopausal osteoporotic mice model

Background: Crocin is a well-known carotenoid with established anti-inflammatory, anti-arthritic, anti-tumor, and antioxidant properties. Previous studies have also identified crocin as a potential drug candidate for osteoporosis treatment; however, the mechanisms underlying its direct influence on...

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Bibliographic Details
Main Authors: Zaffar Azam, Leena Sapra, Asha Bhardwaj, Sumedha Yadav, Pradyumna K. Mishra, Prashant Shukla, Versha Sharma, Rupesh K. Srivastava
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Phytomedicine Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031322000859