7T MRI and molecular studies of Dotarem (gadoterate meglumine) retention in macrophages.

7T MRI and molecular studies of Dotarem (gadoterate meglumine) retention in macrophages.

Gadolinium-based MRI contrast agent Dotarem is commonly used in the clinic. Free Gd3+ is very toxic. Because the crystallographic radius of Gd3+ and Ca2+ is very similar, Gd3+ can compete with Ca2+ in the regulations of cellular functions. Gadolinium is retained in organs and tissues, but the effect...

Full description

Bibliographic Details
Main Authors: Ahmed Uosef, Arijita Subuddhi, Annie Lu, Henry V. Ubelaker, Christof Karmonik, Jarek Wosik, Rafik M. Ghobrial, Malgorzata Kloc
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Magnetic Resonance Open
Subjects:
Magnetic resonance imaging
7T MRI
Dotarem
Gadolinium
Retention
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2666441022000553

Internet

http://www.sciencedirect.com/science/article/pii/S2666441022000553

Similar Items