Uncovering the mechanism of Qidan Dihuang Granule in the treatment of diabetic kidney disease combined network pharmacology, UHPLC-MS/MS with experimental validation

Uncovering the mechanism of Qidan Dihuang Granule in the treatment of diabetic kidney disease combined network pharmacology, UHPLC-MS/MS with experimental validation

Background and aim: Diabetic Kidney Disease (DKD) is a common microvascular complication of diabetes mellitus. Multi-center, randomized controlled trials have shown that Qidan Dihuang Granule (QDDHG) reduces the levels of albuminuria of DKD. However, the specific mechanisms of QDDHG on DKD are not c...

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Bibliographic Details
Main Authors: Lei Xiang, Xiangsheng Cai, Xiaoshan Zhao, Yuanling Liu, Ya Xiao, Pingping Jiang, Lianghong Yin, Dan Song, Xuefeng Jiang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Qidan Dihuang Granule
Diabetic kidney disease
Network pharmacology
Experimental verification
Traditional Chinese medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023089223

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http://www.sciencedirect.com/science/article/pii/S2405844023089223

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