LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease

Abstract Endothelial dysfunction is common in patients with chronic kidney disease (CKD), but the mechanism is unknown. In this study, we found that the circulating ANRIL level was increased and correlated with vascular endothelial dysfunction in patients with CKD, also negatively correlated with pl...

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Bibliographic Details
Main Authors: Hong Su, Bing Liu, Huimin Chen, Tingwei Zhang, Tongtong Huang, Yue Liu, Cheng Wang, Qiqi Ma, Qianhui Wang, Zhimei Lv, Rong Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05068-1