Zinc-Dependent Histone Deacetylases in Lung Endothelial Pathobiology

Zinc-Dependent Histone Deacetylases in Lung Endothelial Pathobiology

A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and, as such, provides a semi-selective barrier between the blood and the interstitial space. Compromise of the lung EC barrier due to inflammatory or toxic events may result in pulmonary edema, which is a cardinal feature of ac...

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Bibliographic Details
Main Authors: Rahul S. Patil, McKenzie E. Maloney, Rudolf Lucas, David J. R. Fulton, Vijay Patel, Zsolt Bagi, Anita Kovacs-Kasa, Laszlo Kovacs, Yunchao Su, Alexander D. Verin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
lung vascular endothelium
endothelial barrier integrity
zinc-dependent HDACs
deacetylation
HDAC inhibitors
acute lung injury
Online Access:https://www.mdpi.com/2218-273X/14/2/140

Internet

https://www.mdpi.com/2218-273X/14/2/140

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