NF-κB as an Inducible Regulator of Inflammation in the Central Nervous System

The NF-κB (nuclear factor K-light-chain-enhancer of activated B cells) transcription factor family is critical for modulating the immune proinflammatory response throughout the body. During the resting state, inactive NF-κB is sequestered by IκB in the cytoplasm. The proteasomal degradation of IκB a...

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Bibliographic Details
Main Authors: Sudha Anilkumar, Elizabeth Wright-Jin
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/6/485