The dCas9-based genome editing in Plasmodium yoelii

The dCas9-based genome editing in Plasmodium yoelii

ABSTRACTGenetic editing is a powerful tool for functional characterization of genes in various organisms. With its simplicity and specificity, the CRISPR-Cas9 technology has become a popular editing tool, which introduces site-specific DNA double-strand breaks (DSBs), and then leverages the endogeno...

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Bibliographic Details
Main Authors: Chao Zhang, Shijie Yang, Elvis Quansah, Ziyu Zhang, Weiran Da, Bingjie Wang
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mSphere
Subjects:
malaria
Plasmodium parasites
CRISPR-Cas9
microbial single-strand annealing proteins
dCas9-SSAP
Online Access:https://journals.asm.org/doi/10.1128/msphere.00095-24

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https://journals.asm.org/doi/10.1128/msphere.00095-24

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