Effect of a Fusion Peptide by Covalent Conjugation of a Mitochondrial Cell-Penetrating Peptide and a Glutathione Analog Peptide

Effect of a Fusion Peptide by Covalent Conjugation of a Mitochondrial Cell-Penetrating Peptide and a Glutathione Analog Peptide

Previously, we designed and synthesized a library of mitochondrial antioxidative cell-penetrating peptides (mtCPPs) superior to the parent peptide, SS31, to protect mitochondria from oxidative damage. A library of antioxidative glutathione analogs called glutathione peptides (UPFs), exceptional in h...

Full description

Bibliographic Details
Main Authors: Carmine Pasquale Cerrato, Ülo Langel
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
antioxidants
cell-penetrating peptides
glutathione analogs
superoxide anion scavenging
mitochondrial targeting
mitochondrial membrane potential
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300657

Internet

http://www.sciencedirect.com/science/article/pii/S2329050117300657

Similar Items