Glutamate and GABAA receptor crosstalk mediates homeostatic regulation of neuronal excitation in the mammalian brain

Glutamate and GABAA receptor crosstalk mediates homeostatic regulation of neuronal excitation in the mammalian brain

Abstract Maintaining a proper balance between the glutamate receptor-mediated neuronal excitation and the A type of GABA receptor (GABAAR) mediated inhibition is essential for brain functioning; and its imbalance contributes to the pathogenesis of many brain disorders including neurodegenerative dis...

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Bibliographic Details
Main Authors: Ya Wen, Zhifang Dong, Jun Liu, Peter Axerio-Cilies, Yehong Du, Junjie Li, Long Chen, Lu Zhang, Lidong Liu, Jie Lu, Ning Zhou, Dong Chuan Wu, Yu Tian Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01148-y

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https://doi.org/10.1038/s41392-022-01148-y

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