Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice

Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice

Scope: Gut microbiome-derived metabolites are the major mediators of diet-induced host-microbial interactions. Aryl hydrocarbon receptor (AHR) plays a crucial role in glucose, lipid, and cholesterol metabolism in the liver. In this study, we aimed to investigate the role of indole-3-acetic acid (IAA...

Full description

Bibliographic Details
Main Authors: Xiuxiu Xu, Siyuan Sun, Ling Liang, Chenxi Lou, Qijin He, Maojuan Ran, Lu Zhang, Jingyue Zhang, Chen Yan, Hengjie Yuan, Lu Zhou, Xin Chen, Xin Dai, Bangmao Wang, Jie Zhang, Jingwen Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Nutrition
Subjects:
NAFLD
AHR
indole-3-acetic acid
sulforaphane
gut microbiota
high-fat diet
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.756565/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.756565/full

Similar Items