Phosphorylated histone variant γH2Av is associated with chromatin insulators in Drosophila.

Chromatin insulators are responsible for orchestrating long-range interactions between enhancers and promoters throughout the genome and align with the boundaries of Topologically Associating Domains (TADs). Here, we demonstrate an association between gypsy insulator proteins and the phosphorylated...

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Bibliographic Details
Main Authors: James R Simmons, Ran An, Bright Amankwaa, Shannon Zayac, Justin Kemp, Mariano Labrador
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010396