Analysis of clinical outcomes and meiotic segregation modes following preimplantation genetic testing for structural rearrangements using aCGH/NGS in couples with balanced chromosome rearrangement

Analysis of clinical outcomes and meiotic segregation modes following preimplantation genetic testing for structural rearrangements using aCGH/NGS in couples with balanced chromosome rearrangement

Abstract Purpose To retrospectively evaluate the effectiveness of PGT‐SR by array comparative genomic hybridization (aCGH) or next‐generation sequencing (NGS) in preventing recurrent miscarriages. Methods Thirty one couples with balanced translocation who underwent 68 PGT‐SR cycles between 2012 and...

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Bibliographic Details
Main Authors: Tatsuya Nakano, Michiko Ammae, Manabu Satoh, Satoshi Mizuno, Yoshiharu Nakaoka, Yoshiharu Morimoto
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Reproductive Medicine and Biology
Subjects:
aCGH/NGS
meiotic segregation mode
PGT‐SR
recurrent miscarriage
Online Access:https://doi.org/10.1002/rmb2.12476

Internet

https://doi.org/10.1002/rmb2.12476

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