Characterization of nodal/TGF-lefty signaling pathway gene variants for possible roles in congenital heart diseases.

Characterization of nodal/TGF-lefty signaling pathway gene variants for possible roles in congenital heart diseases.

BACKGROUND: Nodal/TGF-Lefty signaling pathway has important effects at early stages of differentiation of human embryonic stem cells in directing them to differentiate into different embryonic lineages. LEFTY, one of transforming growth factors in the Nodal/TGF-Lefty signaling pathway, plays an impo...

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Bibliographic Details
Main Authors: Xia Deng, Jing Zhou, Fei-Feng Li, Peng Yan, Er-Ying Zhao, Ling Hao, Kai-Jiang Yu, Shu-Lin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4128709?pdf=render

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http://europepmc.org/articles/PMC4128709?pdf=render

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