Listeria monocytogenes folate metabolism is required to generate N-formylmethionine during infection
ABSTRACT Folic acid and its derivatives are required for the synthesis of purines, pyrimidines, and some amino acids. Antifolate antibiotics that target the folic acid metabolism pathway are commonly used for the treatment of listeriosis caused by the intracellular pathogen Listeria monocytogenes (L...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-10-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.01385-23 |