Fluconazole induces rapid high-frequency MTL homozygosis with microbiological polymorphism in Candida albicans

Background: Candida albicans, a common fungal pathogen that can cause opportunistic infections, is regarded as an apparently asexual, diploid fungus. A parasexual cycle was previously found between homozygotes with opposite mating type-like loci (MTLa/α). Fluconazole-resistant strains had a higher...

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Main Authors: Tsong-Yih Ou, Fang-Mo Chang, Wei-Ning Cheng, Adela Lara, Ming-Li Chou, Wei-Fang Lee, Kai-Cheng Lee, Che-Tong Lin, Wen-Sen Lee, Fang-Lan Yu, Ching-Hua Su
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118216000104