NF-κB RelA is a cell-intrinsic metabolic checkpoint restricting glycolysis

Abstract An intrinsic link between metabolism and function in immune cells, and in particular macrophages, has been well established recently. However, the molecular mechanisms controlling the metabolic switch in these sentinel cells for their integral roles in host defense, inflammation, homeostasi...

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Bibliographic Details
Main Authors: Liwen Li, Lei Han, Zhaoxia Qu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-024-01196-7