Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis

Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis

Background: Rutaecarpine (RUT), a major quinazolino carboline alkaloid compound from the dry unripe fruit Tetradium ruticarpum (A. Juss.) T. G. Hartley, has various pharmacological effects. The aim of this present study was to investigate the potential gastroprotective effect of rutaecarpine on etha...

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Bibliographic Details
Main Authors: Sichen Ren, Ying Wei, Ruilin Wang, Shizhang Wei, Jianxia Wen, Tao Yang, Xing Chen, Shihua Wu, Manyi Jing, Haotian Li, Min Wang, Yanling Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
rutaecarpine
ethanol
gastric mucosal injury
anti-inflammation
anti-oxidation
anti-apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.600295/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.600295/full

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