Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes

IL6 expression in the bone marrow is associated with reduced survival in paediatric AML. Here, the authors used RNA-seq to identify treatment resistance-associated co-occurring inflammatory signalling in leukemic cells.

Bibliographic Details
Main Authors: Hamid Bolouri, Rhonda E. Ries, Alice E. Wiedeman, Tiffany Hylkema, Sheila Scheiding, Vivian H. Gersuk, Kimberly O’Brien, Quynh-Anh Nguyen, Jenny L. Smith, S. Alice Long, Soheil Meshinchi
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34965-4