A Retrospective Cohort Study of Total Colonic Aganglionosis: Is the Appendix a Reliable Diagnostic Tool?

Background: Hirschsprung’s disease (HD) is characterized by a lack of ganglion cells in the myenteric and submucosal plexus, associated with increased numbers of acetyl cholinesterase (AChE) positive nerve fibres. In approximately 10% of patients with HD the entire colon will be affected; a conditio...

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Bibliographic Details
Main Authors: Thomas Joseph O'Hare, Michael McDermott, Maureen O'Sullivan, Pat Dicker, Brice Antao
Format: Article
Language:English
Published: EL-Med-Pub 2020-07-01
Series:Journal of Neonatal Surgery
Subjects:
Online Access:https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/310