The Fatal Circle of NETs and NET-Associated DAMPs Contributing to Organ Dysfunction

The Fatal Circle of NETs and NET-Associated DAMPs Contributing to Organ Dysfunction

The innate immune system is the first line of defense against invading pathogens or sterile injuries. Pattern recognition receptors (PRR) sense molecules released from inflamed or damaged cells, or foreign molecules resulting from invading pathogens. PRRs can in turn induce inflammatory responses, c...

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Bibliographic Details
Main Authors: Helena Block, Jan Rossaint, Alexander Zarbock
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
neutrophil extracellular traps
damage associated molecular pattern
inflammation
innate immune response
remote organ damage
HMGB1
Online Access:https://www.mdpi.com/2073-4409/11/12/1919

Internet

https://www.mdpi.com/2073-4409/11/12/1919

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