HbF Levels in Sickle Cell Disease Are Associated with Proportion of Circulating Hematopoietic Stem and Progenitor Cells and CC-Chemokines

HbF Levels in Sickle Cell Disease Are Associated with Proportion of Circulating Hematopoietic Stem and Progenitor Cells and CC-Chemokines

The concentration of circulating hematopoietic stem and progenitor cells has not been studied longitudinally. Here, we report that the proportions of Lin-CD34+38- hematopoietic multipotent cells (HMCs) and of Lin-CD34+CD38+ hematopoietic progenitors cells (HPCs) are highly variable between individua...

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Bibliographic Details
Main Authors: Caterina P. Minniti, Seda S. Tolu, Kai Wang, Zi Yan, Karl Robert, Shouping Zhang, Andrew S. Crouch, Joan Uehlinger, Deepa Manwani, Eric E. Bouhassira
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
sickle cell disease
hematopoietic stem and progenitor
chemokine
fetal hemoglobin
Online Access:https://www.mdpi.com/2073-4409/9/10/2199

Internet

https://www.mdpi.com/2073-4409/9/10/2199

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