Prdm6 controls heart development by regulating neural crest cell differentiation and migration

Prdm6 controls heart development by regulating neural crest cell differentiation and migration

The molecular mechanisms that drive the acquisition of distinct neural crest cell (NCC) fates is still poorly understood. Here, we identified Prdm6 as an epigenetic modifier that temporally and spatially regulates the expression of NCC specifiers and determines the fate of a subset of migrating card...

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Bibliographic Details
Main Authors: Lingjuan Hong, Na Li, Victor Gasque, Sameet Mehta, Lupeng Ye, Yinyu Wu, Jinyu Li, Andreas Gewies, Jürgen Ruland, Karen K. Hirschi, Anne Eichmann, Caroline Hendry, David van Dijk, Arya Mani
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-03-01
Series:JCI Insight
Subjects:
Cardiology
Development
Online Access:https://doi.org/10.1172/jci.insight.156046

Internet

https://doi.org/10.1172/jci.insight.156046

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