Dynamics and Molecular Interactions of GPI-Anchored CD59

CD59 is a GPI-anchored cell surface receptor that serves as a gatekeeper to controlling pore formation. It is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. While CD59 blocks MAC pores, the receptor is co-opted by bacter...

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Bibliographic Details
Main Authors: Tomas B. Voisin, Emma C. Couves, Edward W. Tate, Doryen Bubeck
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/15/7/430