Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma.

PURPOSE:To test the hypothesis that optic nerve head (ONH) deformation manifesting as changes in its mean surface height precedes thinning of the peripapillary retinal nerve fiber layer (RNFL) in experimental glaucoma (EG). METHODS:68 rhesus macaque monkeys each had three or more baseline imaging se...

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Bibliographic Details
Main Authors: Brad Fortune, Juan Reynaud, Lin Wang, Claude F Burgoyne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808404?pdf=render