Piezo activity levels need to be tightly regulated to maintain normal morphology and function in pericardial nephrocytes

Abstract Due to their position on glomerular capillaries, podocytes are continuously counteracting biomechanical filtration forces. Most therapeutic interventions known to generally slow or prevent the progression of chronic kidney disease appear to lower these biomechanical forces on podocytes, hig...

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Bibliographic Details
Main Authors: Kristina Schulz, Paris Hazelton-Cavill, Karl K. Alornyo, Ilka Edenhofer, Maja Lindenmeyer, Christian Lohr, Tobias B. Huber, Barry Denholm, Sybille Koehler
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-79352-9