Selection of novel human scFvs against cancer antigen IL1RAP by phage and yeast surface display technology

The objective of this study was isolation of humanized single-chain variable fragment (scFv) antibodies against IL1RAP, a promising cancer marker in leukemia and other tumors. Here, we screened for antibody fragments that recognized IL1RAP using a phage-display library of humanized scFv through seve...

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Bibliographic Details
Main Authors: Shixin Duan, Yanrong Jia, Debao Xie, Shenglin Xiao, Cheng Zhou, Fanli Zeng
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2020.1738957