Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma

BackgroundThe infiltration and activation of immune cells in the tumor microenvironment (TIME) affect the prognosis of patients with cancer. Tertiary lymphoid structure (TLS) formation favors tumour- infiltrating-lymphocyte (TIL) recruitment and is regarded as an important indicator of good prognosi...

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Bibliographic Details
Main Authors: Hua Zhao, Yu Zhao, Siyuan Zhang, Zhe Wang, Wenwen Yu, Nan Dong, Xuena Yang, Xiying Zhang, Qian Sun, Xishan Hao, Xiubao Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1302751/full