Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment

Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment

BackgroundImmune-checkpoint inhibitors (ICIs) represent a revolution in cancer therapy and are currently implemented as standard therapy within several cancer indications. Nevertheless, the treatment is only effective in a subset of patients, and immune-related adverse effects complicate the improve...

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Bibliographic Details
Main Authors: Ane Sager Longva, Kristian Berg, Anette Weyergang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
immune check point inhibitor (ICI)
photodynamic therapy
photochemical internalization (PCI)
vascular targeting
immunogenic cell death (ICD)
targeted toxin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1278000/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1278000/full

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