The pair ceramide 1-phosphate/ceramide kinase regulates intracellular calcium and progesterone-induced human sperm acrosomal exocytosis

The pair ceramide 1-phosphate/ceramide kinase regulates intracellular calcium and progesterone-induced human sperm acrosomal exocytosis

Before fertilization, spermatozoa must undergo calcium-regulated acrosome exocytosis in response to physiological stimuli such as progesterone and zona pellucida. Our laboratory has elucidated the signaling cascades accomplished by different sphingolipids during human sperm acrosomal exocytosis. Rec...

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Bibliographic Details
Main Authors: Cintia C. Vaquer, Laila Suhaiman, Martín A. Pavarotti, Rodolfo J. Arias, Anahí B. Pacheco Guiñazú, Gerardo A. De Blas, Silvia A. Belmonte
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human sperm
ceramide 1-phosphate/ceramide kinase
acrosome exocytosis
calcium channels
sphingolipids
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1148831/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1148831/full

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