Development of Synergetic Combinations of a Novel Apoptosis Inducer with AKT and Hsp90 Selective Inhibitors Targeting Hormone-Sensitive and Hormone-Resistant Breast Cancer Cells

Development of Synergetic Combinations of a Novel Apoptosis Inducer with AKT and Hsp90 Selective Inhibitors Targeting Hormone-Sensitive and Hormone-Resistant Breast Cancer Cells

Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]

Bibliographic Details
Main Authors: Diana I. Salnikova, Stepan K. Krymov, Danila V. Sorokin, Fedor B. Bogdanov, Olga E. Andreeva, Alvina I. Khamidullina, Andrey E. Shchekotikhin, Alexander M. Scherbakov
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Proceedings
Subjects:
MCF7 breast cancer cell line
isatin-5-sulfonamides
4-hydroxytamoxifen
AKT Inhibitor IV
antiproliferative effect
resistance
Online Access:https://www.mdpi.com/2504-3900/100/1/4

Internet

https://www.mdpi.com/2504-3900/100/1/4

Similar Items