Both Feline Coronavirus Serotypes 1 and 2 Infected Domestic Cats Develop Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain: Its Implication to Pan-CoV Vaccine Development

Both Feline Coronavirus Serotypes 1 and 2 Infected Domestic Cats Develop Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain: Its Implication to Pan-CoV Vaccine Development

The current study was initiated when our specific-pathogen-free laboratory toms developed unexpectedly high levels of cross-reactive antibodies to human SARS-CoV-2 (SCoV2) receptor binding domain (RBD) upon mating with feline coronavirus (FCoV)-positive queens. Multi-sequence alignment analyses of S...

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Bibliographic Details
Main Authors: Janet K. Yamamoto, Lekshmi K. Edison, Dawne K. Rowe-Haas, Tomomi Takano, Chen Gilor, Chiquitha D. Crews, Apichai Tuanyok, Ananta P. Arukha, Sayaka Shiomitsu, Heather D. S. Walden, Tsutomu Hohdatsu, Stephen M. Tompkins, John G. Morris Jr., Bikash Sahay, Subhashinie Kariyawasam
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
SARS-CoV-2
feline coronavirus
receptor binding domain
cross-reactivity
Online Access:https://www.mdpi.com/1999-4915/15/4/914

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https://www.mdpi.com/1999-4915/15/4/914

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