Pre-analytical processing of plasma and serum samples for combined proteome and metabolome analysis

Metabolomic and proteomic analyses of human plasma and serum samples harbor the power to advance our understanding of disease biology. Pre-analytical factors may contribute to variability and bias in the detection of analytes, especially when multiple labs are involved, caused by sample handling, pr...

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Main Authors: Hagen M. Gegner, Thomas Naake, Aurélien Dugourd, Torsten Müller, Felix Czernilofsky, Georg Kliewer, Evelyn Jäger, Barbara Helm, Nina Kunze-Rohrbach, Ursula Klingmüller, Carsten Hopf, Carsten Müller-Tidow, Sascha Dietrich, Julio Saez-Rodriguez, Wolfgang Huber, Rüdiger Hell, Gernot Poschet, Jeroen Krijgsveld
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.961448/full