DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis

DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis

IntroductionNeutrophil extracellular traps (NETs) have various beneficial and detrimental effects in the body. It has been reported that some bacteria may evade the immune system when entangled in NETs. Thus, the aim of the current study was to evaluate the effects of a combined DNase and antibiotic...

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Bibliographic Details
Main Authors: Jan-Fritjof Willemsen, Julia Wenskus, Moritz Lenz, Holger Rhode, Madgalena Trochimiuk, Birgit Appl, Laia Pagarol-Raluy, Daniela Börnigen, Corinna Bang, Konrad Reinshagen, Martin Herrmann, Julia Elrod, Michael Boettcher
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
appendicitis
abdominal sepsis
biomarker
prospective
neutrophils
extracellular traps
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254838/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254838/full

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