Induction and destruction of folding motifs in cyclotides by cyclic cystine knots

Induction and destruction of folding motifs in cyclotides by cyclic cystine knots

Multivariate roles of cyclic cystine knots (CCK) present in cyclotides are well known. More than often this marvellous combination of disulphide linkages embedded in a macrocyclic backbone is seen to induce and stabilize otherwise unfavourable secondary structural motifs in peptides. Partial or comp...

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Bibliographic Details
Main Authors: Jayapriya Venkatesan, Durba Roy
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Chemical Physics Impact
Subjects:
Molecular dynamics
Cyclotides
Cyclic cystine knot
Principal component analysis
Frustrated
Online Access:http://www.sciencedirect.com/science/article/pii/S266702242300169X

Internet

http://www.sciencedirect.com/science/article/pii/S266702242300169X

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