Fusion of the Mycobacterium tuberculosis antigen 85A to an oligomerization domain enhances its immunogenicity in both mice and non-human primates.
To prevent important infectious diseases such as tuberculosis, malaria and HIV, vaccines inducing greater T cell responses are required. In this study, we investigated whether fusion of the M. tuberculosis antigen 85A to recently described adjuvant IMX313, a hybrid avian C4bp oligomerization domain,...
Հիմնական հեղինակներ: | , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Public Library of Science (PLoS)
2012-01-01
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Շարք: | PLoS ONE |
Առցանց հասանելիություն: | http://europepmc.org/articles/PMC3314664?pdf=render |